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MedicineCancer BiologyOncologyCancer PharmacologyMolecular OncologyOncogenesOncogenic Signaling PathwaysRas Family OncogenesTargeted Cancer TherapyTumor Suppressor GenesBraf V600 MutationsCdk InhibitorsCdk4/6 DysregulationCdk4/6 HyperactivationCyclin RegulationCyclin-dependent Kinase 4/6 InhibitorsProtein Kinase InhibitorsRaf Signaling
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Mutations of the BRAF gene in human cancer
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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
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