Ex vivo‐expanded baboon <scp>CD</scp>39 + regulatory T cells prevent rejection of porcine islet xenografts in <scp>NOD</scp>‐<scp>SCID IL</scp>‐2rγ<sup>−/−</sup> mice reconstituted with baboon peripheral blood mononuclear cells - Concepedia

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Ex vivo‐expanded baboon <scp>CD</scp>39 + regulatory T cells prevent rejection of porcine islet xenografts in <scp>NOD</scp>‐<scp>SCID IL</scp>‐2rγ<sup>−/−</sup> mice reconstituted with baboon peripheral blood mononuclear cells

15

Citations

28

References

2017

Year

Dandan Huang, Ya Wang, Wayne J. Hawthorne, Min Hu, J. Hawkes, Heather Burns, Sussan Davies, Feng Gao, Yi Vee Chew, Shounan Yi,

Xenotransplantation

Abstract

Our data supports the capacity of ex vivo expanded CD39+ baboon Treg to suppress islet xenograft rejection in primatized mice, suggesting it has potential as an adjunctive immunotherapy in preclinical NHP models of xenotransplantation.

References

	Year	Citations

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