The bacterial condensin MukB compacts DNA by sequestering supercoils and stabilizing topologically isolated loops

Multigene Editing in the Escherichia coli Genome via the CRISPR-Cas9 System

Yu Jiang, Biao Chen, Chunlan Duan et al. · Applied and Environmental Microbiology · 2015 · 1.4K citations · Full text

Life Sciences, Biotechnology, Genetics +13

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

Martin Gellert, Kiyoshi Mizuuchi, M H O'Dea et al. · Proceedings of the National Academy of Sciences · 1976 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.

Martin Gellert, M H O'Dea, Toshiki Itoh et al. · Proceedings of the National Academy of Sciences · 1976 · 729 citations

Life Sciences, Microbiology, Molecular Biology +14

The cohesin ring concatenates sister DNA molecules

Christian H. Haering, Ana-Maria Farcas, Prakash Arumugam et al. · Nature · 2008 · 524 citations

Life Sciences, Genetics, Molecular Biology +11

Entropy-driven spatial organization of highly confined polymers: Lessons for the bacterial chromosome

Suckjoon Jun, Bela M. Mulder · Proceedings of the National Academy of Sciences · 2006 · 423 citations · Full text

Natural Sciences, Biophysics, Microbiology +17