Concepedia

Hinge Region Structure

Hinge Region Structure is a structural domain in immunoglobulin molecules that functions as a flexible peptide segment connecting the Fab and Fc regions of an antibody, thereby enabling proper spatial orientation and independent movement of antigen-binding fragments.

1K

Publications

63.8K

Citations

5.3K

Authors

1.2K

Institutions

Publications per year

2017–2026

137

Variants

Hinge Region

Parents

Publications

1K

Predicting Coiled Coils from Protein Sequences

Andrei N. Lupas, Marc Van Dyke, Jeff Stock · Science · 1991 · 4K citations

, , +15

Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors

Moosa Mohammadi, Gerald McMahon, Li Sun et al. · Science · 1997 · 1.1K citations · Full text

, , +17

Specific Binding of Nisin to the Peptidoglycan Precursor Lipid II Combines Pore Formation and Inhibition of Cell Wall Biosynthesis for Potent Antibiotic Activity

Imke Wiedemann, Eefjan Breukink, Cindy van Kraaij et al. · Journal of Biological Chemistry · 2001 · 775 citations · Full text

, , +16

Convergent Solutions to Binding at a Protein-Protein Interface

Warren L. DeLano, Mark Ultsch, Abraham M. de et al. · Science · 2000 · 682 citations

, , +17

Membrane estrogen receptors identified by multiple antibody labeling and impeded‐ligand binding

Todd C. Pappas, Bahiru Gametchu, Cheryl S. Watson · The FASEB Journal · 1995 · 530 citations

, , +17

1–5 of 1K

Authors

5.3K

  1. TE
    Terje E. Michaelsen

    University of Oslo, Norway

    18 publications · 1K citations

    15

    h-index

  2. MK
    Mogens Kilian

    Aarhus University, Denmark

    13 publications · 975 citations

    12

    h-index

  3. HI
    Hitoo Iwase

    Kitasato University, Japan

    10 publications · 752 citations

    10

    h-index

  4. BF
    Blas Frangione

    New York University, United States

    10 publications · 498 citations

    10

    h-index

  5. TK
    Tohru Kokubo

    Kitasato University, Japan

    9 publications · 680 citations

    9

    h-index

1–5 of 5.3K

Institutions

1.2K

  1. The University of Tokyo

    Tokyo, Japan

    18 h-index

    93 publications

    5.5K citations

  2. University of Oxford

    Oxford, United Kingdom

    17 h-index

    68 publications

    9.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    86 publications

    5.3K citations

  4. Harvard University

    Cambridge, United States

    17 h-index

    92 publications

    7K citations

  5. Inserm

    Paris, France

    17 h-index

    95 publications

    3.6K citations

  6. University of Alabama at Birmingham

    Birmingham, United States

    15 h-index

    68 publications

    4.4K citations

  7. National Institutes of Health

    Bethesda, United States

    15 h-index

    54 publications

    2.9K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    37 publications

    2.4K citations

1–8 of 1.2K

Venues

  1. Journal of Biological Chemistry

    JBC · 122 publications · 9.4K citations

    53

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 61 publications · 4.7K citations

    41

    h-index

  3. Biochemistry

    72 publications · 3.7K citations

    34

    h-index

  4. The Journal of Immunology

    JI · 30 publications · 1.8K citations

    20

    h-index

  5. European Journal of Biochemistry

    EJB · 22 publications · 1.2K citations

    18

    h-index

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