Concepedia

Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells

X-X Li, H-S Zhang, Y-M Xu, R-J Zhang, Y. Chen, Liangqianjin Fan, Y-Q Qin, Yuan‐Tong Liu, Miao Li, J. Fang

Oncogene · 2017 · 78 citations · 30 references

DOI

Concepts

References

30

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

, , +14

Patterns of somatic mutation in human cancer genomes

Christopher Greenman, Philip Stephens, Raffaella Smith et al. · Nature · 2007 · 3.1K citations · Full text

, , +14

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Louis Vermeulen, Felipe de Sousa e Melo, Maartje van der Heijden et al. · Nature Cell Biology · 2010 · 1.8K citations

, , +10

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

Jeffery S. Cox, Caroline E. Shamu, Peter Walter · Cell · 1993 · 1.2K citations

, , +8

A transmembrane protein with a cdc2+CDC28-related kinase activity is required for signaling from the ER to the nucleus

Kazutoshi Morl, Wenzhen Ma, Mary‐Jane Gething et al. · Cell · 1993 · 821 citations

, , +9