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Sepsis prediction in critically ill patients by platelet activation markers on ICU admission: a prospective pilot study

Nathalie Layios, Céline Delierneux, Alexandre Hego, Justine Huart, Christian Gosset, Christelle Lecut, Nathalie Maes, Pierre Geurts, Arnaud Joly, Patrizio Lancellotti,

Intensive Care Medicine Experimental · 2017 · 32 citations · 35 references

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Abstract

Platelet-bound fibrinogen levels assayed by flow cytometry within 24 h of ICU admission help identifying critically ill patients at risk of developing sepsis.

References

35

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mervyn Singer, Clifford S. Deutschman, Christopher W. Seymour et al. · JAMA · 2016 · 26.3K citations · Full text

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Stephen Clark, C. Adrienne, Samantha A. Tavener et al. · Nature Medicine · 2007 · 2.2K citations

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Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation

Oliver Borst, Britta Walker, Patrick Münzer et al. · Cellular Physiology and Biochemistry · 2013 · 1.9K citations · Full text

The role of platelets in inflammation

Thrombosis and Haemostasis · 2015 · 516 citations

Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo

Rukhsana Aslam, Edwin R. Speck, Michael D. Kim et al. · Blood · 2005 · 473 citations · Full text