Concepedia

Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity

Chao Zhang, Jun Du, Zhiyong Zhuo, Shuo Yang, Wei‐Hong Zhang, Weihong Wang, Shengyuan Zhang, Yoichiro Iwakura, Guangxun Meng, Yang‐Xin Fu,

Cellular and Molecular Immunology · 2017 · 100 citations · 53 references

DOI

Concepts

References

53

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

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Non-canonical inflammasome activation targets caspase-11

Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi et al. · Nature · 2011 · 2.5K citations

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ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. I. ROLE OF DRUG METABOLISM

John R. Mitchell, David J. Jollow, William Z. Potter et al. · Journal of Pharmacology and Experimental Therapeutics · 1973 · 1.5K citations

, , +17

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

Chun‐Jen Chen, Hajime Kono, Douglas T. Golenbock et al. · Nature Medicine · 2007 · 855 citations

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CD24 and Siglec-10 Selectively Repress Tissue Damage–Induced Immune Responses

Guo‐Yun Chen, Jie Tang, Pan Zheng et al. · Science · 2009 · 777 citations · Full text

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