Concepedia

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

Chun‐Jen Chen, Hajime Kono, Douglas T. Golenbock, George Reed, Shizuo Akira, Kenneth L. Rock

Nature Medicine · 2007 · 855 citations · 23 references

DOI

Concepts

References

23

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Paola Scaffidi, Tom Misteli, Marco E. Bianchi · Nature · 2002 · 4.2K citations

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Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

Elizabeth A. Leadbetter, Ian R. Rifkin, Andreas M. Hohlbaum et al. · Nature · 2002 · 1.9K citations

, , +14

Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme

Keisuke Kuida, Judith A. Lippke, George Ku et al. · Science · 1995 · 1.6K citations

, , +16

Applied longitudinal analysis

Choice Reviews Online · 2004 · 1.4K citations

Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.

Joseph L. Romson, Bruce G. Hook, Steven L. Kunkel et al. · Circulation · 1983 · 1.2K citations

, , +17