Journal of Agricultural and Food Chemistry · 2017 · 62 citations · 37 references
PharmacyBioengineeringPharmaceuticsControlled Release FormulationsDrug DeliveryPharmaceutical FormulationCapsule FormulationDrug EncapsulationEmulsion FormulationEmulsion-based Delivery SystemsMicrocapsule SizePesticide EncapsulationPorosityPremix FormulationSolubilitySurface PorositySurface Porosity Control
Microcapsule formulations have been widely developed and used in agriculture to improve pesticide utilization and reduce environmental pollution. However, commercial formulations of chlorantraniliprole (CAP) are only traditional formulations due to poor solubility of CAP in organic solvents. Here, adopting a solid in oil in water (S/O/W) double-emulsion method combined with premix membrane emulsion, we successfully constructed CAP microcapsule formulations with a high loading content. The microcapsule formulations with good light and thermal stability showed a significantly sustained release for a long period, which could be optimally regulated by tuning the surface porosity and size of the porous microcapsules. Bioassay studies showed that control efficacy of the porous microcapsule formulations against Plutella xylostella was superior to that of the commercial formulation. These results demonstrated that such a porous microcapsule delivery system should have great potential for further exploration as a commercial CAP formulation.
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Controlled pesticide release from biodegradable polymers
Anamika Roy, Sunil Kumar Singh, Jaya Bajpai et al. · Open Chemistry · 2014 · 250 citations · Full text
Pharmacy, Agricultural Engineering, Controlled Release Formulations +16