Harnessing combined p19Arf and interferon-beta gene transfer as an inducer of immunogenic cell death and mediator of cancer immunotherapy

Aline Hunger, Ruan FV Medrano, Bryan E. Strauss

Cell Death and Disease · 2017 · 13 citations · 10 references

DOIFull text

Open access

Concepts

Abstract

Cancer immunotherapy is a wide-ranging term that includes many strategies to reestablish or activate an effector antitumor immunity cycle. Among the most successful approaches, PD-1/PDL-1 and CTLA-4 checkpoint blockade and chimeric antigen receptor (CAR) T cells have provided undeniable evidence of the potential of immunotherapy for several types of cancer, including metastatic melanoma. 1

References

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