Guo Chen

A Landscape of Driver Mutations in Melanoma

Eran Hodis, Ian R. Watson, Gregory V. Kryukov et al. · Cell · 2012 · 2.6K citations · Full text

Medicine, Genetics, Oncology +12

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

Lei Liu, Du Feng, Guo Chen et al. · Nature Cell Biology · 2012 · 1.6K citations

Life Sciences, Biochemistry, Cell Biology +16

Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy

Weiyi Peng, Jie Qing Chen, Chengwen Liu et al. · Cancer Discovery · 2015 · 1.5K citations · Full text

Medicine, Immunology, Oncology +17

A unified model of protein dynamics

Hans Frauenfelder, Guo Chen, Joel Berendzen et al. · Proceedings of the National Academy of Sciences · 2009 · 758 citations · Full text

Natural Sciences, Biophysics, Physics +17

A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy

Guo Chen, Zhe Han, Du Feng et al. · Molecular Cell · 2014 · 567 citations

Life Sciences, Cell Biology, Molecular Biology +16