Interferon Pathway Genes is a genetic construct comprising a set of genes involved in the signaling and response mechanisms of interferons, distinguished by their regulatory roles in innate immunity and their association with susceptibility to autoimmune diseases.
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A diverse range of gene products are effectors of the type I interferon antiviral response
John W. Schoggins, Sam J. Wilson, Maryline Panis et al. · Nature · 2011 · 2.5K citations
Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease
Joan E. Durbin, Renée Hackenmiller, M. Celeste Simon et al. · Cell · 1996 · 1.6K citations · Full text
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