Concepedia

Publication | Open Access

Peripheral complement interactions with amyloid β peptide: Erythrocyte clearance mechanisms

DOIFull Paper Access

49

Citations

41

References

2017

Year

William D. Brubaker, Andrés B Crane, Jenny U. Johansson, Kevin Yen, Kristina Garfinkel, Diego Mastroeni, Priya Asok, Bonnie M. Bradt, Marwan N. Sabbagh, Tanya L. Wallace,
Alzheimer s & Dementia

Abstract

CR1 polymorphisms elevate AD risk, and >80% of human CR1 is vested in erythrocytes to subserve immune adherence. The present results suggest that this pathway is pathophysiologically relevant in AD.

References

YearCitations

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