Concepedia

In vitro and in vivo antitumor activities of T-3764518, a novel and orally available small molecule stearoyl-CoA desaturase 1 inhibitor

Satoru Nishizawa, Hiroyuki Sumi, Yoshihiko Satoh, Yukiko Yamamoto, Satoshi Kitazawa, Kohei Honda, Hideo Araki, Kazuyo Kakoi, Keisuke Imamura, Masako Sasaki,

European Journal of Pharmacology · 2017 · 25 citations · 30 references

DOI

Concepts

References

30

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

E. G. Bligh, W. J. Dyer · Canadian Journal of Biochemistry and Physiology · 1959 · 48.9K citations

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On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma

Christina A. Von Roemeling, Laura A. Marlow, Johnny J. Wei et al. · Clinical Cancer Research · 2013 · 281 citations · Full text

, , +17

Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy

Urvashi V. Roongta, Jonathan G. Pabalan, Xinyu Wang et al. · Molecular Cancer Research · 2011 · 278 citations

, , +17

Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth

B Griffiths, Caroline A. Lewis, Karim Bensaad et al. · Cancer & Metabolism · 2013 · 269 citations · Full text

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