Kazuyo Kakoi

Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds

Masanori Okaniwa, Masaaki Hirose, Takashi Imada et al. · Journal of Medicinal Chemistry · 2012 · 78 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery

Kenichi Iwai, Tadahiro Nambu, Yukie Kashima et al. · Science Advances · 2021 · 27 citations · Full text

Life Sciences, Molecular Biology, Oncology +12

In vitro and in vivo antitumor activities of T-3764518, a novel and orally available small molecule stearoyl-CoA desaturase 1 inhibitor

Satoru Nishizawa, Hiroyuki Sumi, Yoshihiko Satoh et al. · European Journal of Pharmacology · 2017 · 25 citations

Medicine, Oncology, Pharmacology +8