Intrinsically Defective Microtubule Dynamics Contribute to Age-Related Chromosome Segregation Errors in Mouse Oocyte Meiosis-I

A mechanism linking extra centrosomes to chromosomal instability

Neil J. Ganem, Susana A. Godinho, David Pellman · Nature · 2009 · 1.4K citations · Full text

Chromatin, Genome Instability, Genetics +5

Fertilization and early embryology: Influence of maternal age on meiotic spindle assembly oocytes from naturally cycling women

David Battaglia, Paul C. Goodwin, Nathan Klein et al. · Human Reproduction · 1996 · 642 citations · Full text

Self-Organization of MTOCs Replaces Centrosome Function during Acentrosomal Spindle Assembly in Live Mouse Oocytes

Melina Schuh, Jan Ellenberg · Cell · 2007 · 569 citations · Full text

Oocyte, Chromatin, Developmental Biology +13

Merotelic Kinetochore Orientation Is a Major Mechanism of Aneuploidy in Mitotic Mammalian Tissue Cells

Daniela Cimini, Bonnie J. Howell, Paul S. Maddox et al. · The Journal of Cell Biology · 2001 · 565 citations · Full text

Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells

William T. Silkworth, Isaac K. Nardi, Lindsey M. Scholl et al. · PLoS ONE · 2009 · 436 citations · Full text

Kinetochore Mis-attachment, Genetics, Molecular Biology +17