Absolute quantification of somatic DNA alterations in human cancer

Scott L. Carter, Kristian Cibulskis, Elena Helman, +13

Nature Biotechnology

A mechanism linking extra centrosomes to chromosomal instability

Neil J. Ganem, Susana A. Godinho, David Pellman

Nature

ChromatinGenome InstabilityGeneticsChromosomal RearrangementExtra Centrosomes +3

DNA breaks and chromosome pulverization from errors in mitosis

Karen Crasta, Neil J. Ganem, Regina Dagher, +7

Nature

ChromatinGenome InstabilityDna DamageCell DivisionMedicine +8

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

Takeshi Fujiwara, Madhavi Bandi, Masayuki Nitta, +3

Nature

MedicineCytokinesis FailureCell DeathTumor SuppressorCancer Biology +2

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Isidro Cortés‐Ciriano, Jake June-Koo Lee, Ruibin Xi, +24

Nature Genetics

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

Mijung Kwon, Susana A. Godinho, Namrata S. Chandhok, +4

Genes & Development

Cell ProliferationCytoskeletonCell CycleExtra CentrosomesCancer Biology +15

Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance

Max A. Tischfield, Hagit Baris, Chen Wu, +46

Cell

Axon GuidanceProtein FunctionMolecular BiologyCytoskeletonCell Motility +6

Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing

Mitchell L. Leibowitz, Stamatis Papathanasiou, Phillip A. Doerfler, +6

Nature Genetics

Crispr–cas9 Genome EditingGeneticsMolecular BiologyGenetic EngineeringGene Editing +3

Polyploidy can drive rapid adaptation in yeast

Anna Selmecki, Yosef E. Maruvka, Phillip A. Richmond, +8

Nature

BiologyRapid AdaptationGeneticsYeastMolecular Genetics +2

An actin nucleation mechanism mediated by Bni1 and Profilin

Isabelle Sagot, Avital A. Rodal, James B. Moseley, +2

Nature Cell Biology

Protein FoldingMacromolecular MachineMolecular BiologyActin Nucleation MechanismCell Motility +2