Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.6K citations · Full text

Molecular Regulation, Immunology, Molecular Biology +23

Design of the linkers which effectively separate domains of a bifunctional fusion protein

Ryoichi Arai, Hiroshi Ueda, A. Kitayama et al. · Protein Engineering Design and Selection · 2001 · 747 citations · Full text

Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase

Frederick S. Buckner, Christophe L. M. J. Verlinde, Anne Camille La Flamme et al. · Antimicrobial Agents and Chemotherapy · 1996 · 525 citations · Full text

Parasitic Disease, Antiparasitic Agent, Malaria +16

Splicing by overlap extension by PCR using asymmetric amplification: an improved technique for the generation of hybrid proteins of immunological interest

Anthony Ν. Warrens, Michael D. Jones, Robert I. Lechler · Gene · 1997 · 285 citations

Rna Processing, Molecular Biological Method, Natural Sciences +13

Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells

Daniela A. Bermejo, Shaun W. Jackson, Melisa Gorosito-Serrán et al. · Nature Immunology · 2013 · 238 citations · Full text

Activated B Cells, African Trypanosomiasis, Il-17 Production +11