Concepedia

Multivalent Antigen Display

Multivalent Antigen Display is a nanoparticle-based immunotechnological strategy that presents multiple copies of antigenic epitopes on a single nanoscale platform to enhance immune recognition and activation through controlled spatial organization and avidity effects.

48

Publications

2.3K

Citations

440

Authors

137

Institutions

Publications per year

2017–2026

28

Parents

Publications

48

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

Philip J. M. Brouwer, Aleksandar Antanasijevic, Zachary T. Berndsen et al. · Nature Communications · 2019 · 213 citations · Full text

, , +17

DARPins Recognizing the Tumor-Associated Antigen EpCAM Selected by Phage and Ribosome Display and Engineered for Multivalency

Nikolas Stefan, Patricia Martin-Killias, Sascha Wyss-Stoeckle et al. · Journal of Molecular Biology · 2011 · 132 citations

, , +14

A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spike alone

Baoshan Zhang, Cara W. Chao, Yaroslav Tsybovsky et al. · Scientific Reports · 2020 · 130 citations · Full text

, , +17

EFFECTOR CELL BLOCKADE

John W. Schrader, G. J. V. Nossal · The Journal of Experimental Medicine · 1974 · 111 citations · Full text

, , +11

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens

Ivelin S. Georgiev, Michael Joyce, Rita E. Chen et al. · ACS Infectious Diseases · 2018 · 93 citations · Full text

, , +17

1–5 of 48

Authors

440

  1. BS
    Barney S. Graham

    National Institute of Allergy and Infectious Diseases, United States

    6 publications · 379 citations

    6

    h-index

  2. NP
    Neil P. King

    University of Washington, United States

    6 publications · 499 citations

    6

    h-index

  3. DB
    David Baker

    University of Washington, United States

    5 publications · 427 citations

    5

    h-index

  4. JR
    John R. Mascola

    National Institute of Allergy and Infectious Diseases, United States

    4 publications · 277 citations

    4

    h-index

  5. YT
    Yaroslav Tsybovsky

    Frederick National Laboratory for Cancer Research, United States

    4 publications · 269 citations

    4

    h-index

1–5 of 440

Institutions

137

  1. University of Washington

    Seattle, United States

    6 h-index

    42 publications

    3.2K citations

  2. National Institutes of Health

    Bethesda, United States

    6 h-index

    83 publications

    5.8K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    6 h-index

    84 publications

    5.8K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    6 publications

    498 citations

  5. Frederick National Laboratory for Cancer Research

    Frederick, United States

    4 h-index

    5 publications

    362 citations

  6. Duke Medical Center

    Durham, United States

    4 h-index

    8 publications

    683 citations

  7. Leidos (United States)

    Reston, United States

    4 h-index

    5 publications

    362 citations

  8. Harvard University

    Cambridge, United States

    3 h-index

    6 publications

    258 citations

1–8 of 137

Venues

  1. Biomaterials

    5 publications · 202 citations

    5

    h-index

  2. Nature Communications

    4 publications · 348 citations

    4

    h-index

  3. Biomacromolecules

    3 publications · 92 citations

    4

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 4 publications · 87 citations

    4

    h-index

  5. Scientific Reports

    3 publications · 178 citations

    3

    h-index

1–5