Concepedia

Immunogen Engineering

Immunogen Engineering is the rational design and modification of immunogenic molecules to elicit specific, targeted, and effective immune responses, distinguished from broader vaccine development approaches by its focus on the structural and functional optimization of antigenic components to enhance immunogenicity, stability, and protective efficacy.

255

Publications

16K

Citations

1.8K

Authors

481

Institutions

Publications per year

2017–2026

83

Parents

Publications

255

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

Jesper Pallesen, Nianshuang Wang, Kizzmekia S. Corbett et al. · Proceedings of the National Academy of Sciences · 2017 · 1.2K citations · Full text

, , +17

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

Antonietta Impagliazzo, Fin Milder, Harmjan Kuipers et al. · Science · 2015 · 625 citations · Full text

, , +17

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

John Steel, Anice C. Lowen, Taia T. Wang et al. · mBio · 2010 · 530 citations · Full text

, , +17

HIV-1 neutralizing antibodies induced by native-like envelope trimers

Rogier W. Sanders, Marit J. van Gils, Ronald Derking et al. · Science · 2015 · 524 citations · Full text

, , +17

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

Joseph G. Jardine, Takayuki Ota, Devin Sok et al. · Science · 2015 · 439 citations

, , +17

1–5 of 255

Authors

1.8K

  1. AB
    Andrew B. Ward

    Scripps Research Institute, United States

    9 publications · 2.8K citations

    9

    h-index

  2. DR
    Dennis R. Burton

    Scripps Research Institute, United States

    8 publications · 2.3K citations

    9

    h-index

  3. IA
    Ian A. Wilson

    Scripps Research Institute, United States

    9 publications · 2.5K citations

    9

    h-index

  4. DC
    David C. Montefiori

    Duke Medical Center, United States

    8 publications · 1.4K citations

    9

    h-index

  5. WR
    William R. Schief

    Scripps Research Institute, United States

    9 publications · 2.4K citations

    9

    h-index

1–5 of 1.8K

Institutions

481

  1. Scripps Research Institute

    San Diego, United States

    20 h-index

    198 publications

    55.4K citations

  2. National Institutes of Health

    Bethesda, United States

    19 h-index

    66 publications

    3.7K citations

  3. Harvard University

    Cambridge, United States

    17 h-index

    48 publications

    5K citations

  4. Ragon Institute of MGH, MIT and Harvard

    Cambridge, United States

    15 h-index

    88 publications

    11.3K citations

  5. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    15 h-index

    48 publications

    8.5K citations

  6. International AIDS Vaccine Initiative

    New York, United States

    14 h-index

    138 publications

    35.7K citations

  7. University of Pennsylvania

    Philadelphia, United States

    12 h-index

    54 publications

    5.4K citations

  8. University of Oxford

    Oxford, United Kingdom

    9 h-index

    41 publications

    879 citations

1–8 of 481

Venues

  1. Vaccine

    16 publications · 573 citations

    14

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 2.4K citations

    12

    h-index

  3. Journal of Virology

    JVI · 9 publications · 521 citations

    9

    h-index

  4. PLoS ONE

    7 publications · 198 citations

    8

    h-index

  5. Nature Communications

    7 publications · 452 citations

    8

    h-index

1–5