Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

Jesper Pallesen, Nianshuang Wang, Kizzmekia S. Corbett, +15

Proceedings of the National Academy of Sciences

ImmunologyViral PathogenesisImmunodominanceMolecular BiologyOptimal Prefusion Conformation +17

Pre-fusion structure of a human coronavirus spike protein

Robert N. Kirchdoerfer, Christopher A. Cottrell, Nianshuang Wang, +7

Nature

Virus StructureMolecular BiologyPre-fusion StructureVirologyViral Structural Protein +2

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

Robert N. Kirchdoerfer, Nianshuang Wang, Jesper Pallesen, +7

Scientific Reports

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

Gabriel Ozorowski, Jesper Pallesen, Natalia de Val, +10

Nature

Virus StructureViral ReplicationProtein FoldingNatural SciencesHuman Retrovirus +11

Trajectories of the ribosome as a Brownian nanomachine

Ali Dashti, Peter Schwander, Robert Langlois, +11

Proceedings of the National Academy of Sciences

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Erica Ollmann Saphire, Sharon L. Schendel, Marnie L. Fusco, +45

Cell

VaccinationVirus EpidemiologyVaccine TargetSystematic AnalysisImmunology +5

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

N.S. Laursen, Robert H. Friesen, Xueyong Zhu, +25

Science

Influenza InfectionImmunologyUniversal ProtectionStrain SelectionMultidomain Antibody +17

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

Marit J. van Gils, Tom L.G.M. van den Kerkhof, Gabriel Ozorowski, +24

Nature Microbiology

Hiv-1 AntibodyHuman RetrovirusFusion PeptideImmunologyAntiviral Response +7

Structure of the human volume regulated anion channel

Jennifer M. Kefauver, Kei Saotome, Adrienne E. Dubin, +10

eLife

Human VolumeHomomeric ChannelMolecular BiologyCytoskeletonCellular Physiology +20

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

Jesper Pallesen, Charles D. Murin, Natalia de Val, +10

Nature Microbiology

Virus StructureMolecular VirologyViral PathogenesisImmunologyMolecular Biology +5