Concepedia

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State

Adelle P. McFarland, Shukun Luo, Fariha Ahmed-Qadri, Meghan Zuck, Elizabeth F. Thayer, Young Ah Goo, Kevin Hybiske, Liang Tong, Joshua J. Woodward

Immunity · 2017 · 121 citations · 38 references

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38

STING is a direct innate immune sensor of cyclic di-GMP

Dara Burdette, Kathryn M. Monroe, Katia Troha et al. · Nature · 2011 · 1.5K citations

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Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

Xu Zhang, Heping Shi, Jiaxi Wu et al. · Molecular Cell · 2013 · 1.1K citations · Full text

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c-di-AMP Secreted by Intracellular <i>Listeria monocytogenes</i> Activates a Host Type I Interferon Response

Joshua J. Woodward, Anthony T. Iavarone, Daniel A. Portnoy · Science · 2010 · 821 citations · Full text

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The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING

Elie J. Diner, Dara Burdette, Stephen C. Wilson et al. · Cell Reports · 2013 · 752 citations · Full text

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The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

Robert O. Watson, Samantha L. Bell, Donna A. MacDuff et al. · Cell Host & Microbe · 2015 · 630 citations · Full text

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