Concepedia

NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma

Zili Zhai, Wen-Ting Liu, Manjinder Kaur, Y. Luo, Joanne Domenico, Jenny Mae Samson, Yiqun G. Shellman, David A. Norris, Charles A. Dinarello, Richard A. Spritz,

Oncogene · 2017 · 125 citations · 33 references

DOI

Concepts

References

33

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

IL-1 is required for tumor invasiveness and angiogenesis

Elena Voronov, Dror S. Shouval, Yakov Krelin et al. · Proceedings of the National Academy of Sciences · 2003 · 1K citations · Full text

, , +17

Reconstituted NALP1 Inflammasome Reveals Two-Step Mechanism of Caspase-1 Activation

Benjamin Faustin, Lydia Lartigue, Jean‐Marie Bruey et al. · Molecular Cell · 2007 · 698 citations · Full text

, , +13

<i>Salmonella</i> induces macrophage death by caspase‐1‐dependent necrosis

Molly A. Brennan, Brad T. Cookson · Molecular Microbiology · 2000 · 681 citations

, , +16

Chronic Inflammation in Cancer Development

Gabriele Multhoff, M. Molls, Jürgen Radons · Frontiers in Immunology · 2012 · 571 citations · Full text

, , +17