Concepedia

Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands

Cynthia Ann Griffith, Adam S. Dayoub, Thamara Jaranatne, Nagham Alatrash, Ali H. Mohamedi, Kenneth Abayan, Zachary S. Breitbach, Daniel W. Armstrong, Frederick M. MacDonnell

Chemical Science · 2017 · 46 citations · 108 references

DOIFull text

Open access

Concepts

Abstract

Yellow foci show time dependent DNA double strand breaks in the nuclei of H358 cells treated with IC<sub>50</sub> concentration of [(phen)<sub>2</sub>Ru(tatpp)Ru(Phen)<sub>2</sub>]Cl<sub>4</sub>.

References

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Hydrogen Peroxide Synthesis: An Outlook beyond the Anthraquinone Process

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