Concepedia

Physiological role of endothelin-1 in flow-mediated vasodilatation in humans and impact of cardiovascular risk factors

Jérémy Bellien, Michèle Iacob, Christelle Monteil, Isabelle Rémy‐Jouet, Clothilde Roche, Thomas Duflot, Cathy Vendeville, Laurence Gutierrez, Christian Thuillez, Vincent Richard,

Journal of Hypertension · 2017 · 12 citations · 30 references

DOI

Abstract

The uptake of endothelin-1 by ETB receptors contributes to conduit artery FMD, preventing its vasoconstrictor action mediated by ETA receptors. The alteration of this mechanism by cardiovascular risk factors may contribute to endothelial dysfunction.

References

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