Concepedia

The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment

James Austerberry, Rana Dajani, Stanislava Panova, Dorota Roberts, Alexander P. Golovanov, Alain Pluen, Christopher F. van der Walle, Shahid Uddin, Jim Warwicker, Jeremy P. Derrick,

European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 57 citations · 86 references

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86

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

F. Niesen, H. Berglund, Masoud Vedadi · Nature Protocols · 2007 · 2.4K citations

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AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

Oscar Conchillo‐Solé, Natalia Sánchez de Groot, Francesc Avilés et al. · BMC Bioinformatics · 2007 · 1.1K citations · Full text

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Biopharmaceutical benchmarks 2014

Gary Walsh · Nature Biotechnology · 2014 · 1K citations

Biopharmaceutical benchmarks 2010

Gary Walsh · Nature Biotechnology · 2010 · 759 citations

Design of therapeutic proteins with enhanced stability

Naresh Chennamsetty, Vladimir Voynov, Veysel Kayser et al. · Proceedings of the National Academy of Sciences · 2009 · 597 citations · Full text

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