Novel exon–exon breakpoint in <i>CIC-DUX4</i> fusion sarcoma identified by anchored multiplex PCR (Archer FusionPlex Sarcoma Panel)

Abstract

This case report describes an additional case of <i>CIC-DUX4</i> sarcoma with a novel fusion breakpoint, and demonstrates the value of this next-generation sequencing-based anchored multiplex PCR technique (Archer FusionPlex Sarcoma Panel) in both diagnosis for patient care and in identification of a novel fusion breakpoint in this tumour type.