Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

Education, Cell Biology, Molecular Biology +15

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Makoto Kuro‐o, Yutaka Matsumura, Hiroki Aizawa et al. · Nature · 1997 · 3.8K citations

Life Sciences, Genetics, Molecular Genetics +12

Suppression of Aging in Mice by the Hormone Klotho

Hiroshi Kurosu, Masaya Yamamoto, Jeremy D. Clark et al. · Science · 2005 · 1.9K citations · Full text

Education, Endocrinology, Genetics +17

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

Yuchen Chien, Claudio Scuoppo, Xiaowo Wang et al. · Genes & Development · 2011 · 1K citations · Full text

Life Sciences, Cell Biology, Oncology +17

Regulation of Oxidative Stress by the Anti-aging Hormone Klotho*♦

Masaya Yamamoto, Jeremy D. Clark, Johanne V. Pastor et al. · Journal of Biological Chemistry · 2005 · 727 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17