Concepedia

Klotho Deficiency

Klotho Deficiency is a pathological condition characterized by insufficient expression or activity of the Klotho protein, a key regulator of phosphate and vitamin D metabolism, leading to accelerated aging phenotypes and renal endocrine dysfunction.

607

Publications

49.1K

Citations

4.1K

Authors

1K

Institutions

Publications per year

2017–2026

286

Parents

Publications

607

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

, , +17

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Makoto Kuro‐o, Yutaka Matsumura, Hiroki Aizawa et al. · Nature · 1997 · 3.8K citations

, , +12

Suppression of Aging in Mice by the Hormone Klotho

Hiroshi Kurosu, Masaya Yamamoto, Jeremy D. Clark et al. · Science · 2005 · 1.9K citations · Full text

, , +17

Regulation of Fibroblast Growth Factor-23 Signaling by Klotho

Hiroshi Kurosu, Yasushi Ogawa, Masayoshi Miyoshi et al. · Journal of Biological Chemistry · 2006 · 1.4K citations · Full text

, , +16

Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease

Ming Chang Hu, Mingjun Shi, Jianning Zhang et al. · Journal of the American Society of Nephrology · 2010 · 923 citations

, , +13

1–5 of 607

Authors

4.1K

  1. MK
    Makoto Kuro‐o

    The University of Texas Southwestern Medical Center, United States

    65 publications · 15.5K citations

    45

    h-index

  2. YN
    Yo‐ichi Nabeshima

    Kyoto University, Japan

    21 publications · 3.4K citations

    20

    h-index

  3. OW
    Orson W. Moe

    The University of Texas Southwestern Medical Center, United States

    18 publications · 4.3K citations

    17

    h-index

  4. ZS
    Zhongjie Sun

    University of Oklahoma Health Sciences Center, United States

    18 publications · 1.5K citations

    17

    h-index

  5. FL
    Florian Läng

    University of Tübingen, Germany

    24 publications · 953 citations

    16

    h-index

1–5 of 4.1K

Institutions

1K

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    45 h-index

    214 publications

    69.1K citations

  2. Kyoto University

    Kyoto, Japan

    26 h-index

    104 publications

    14.5K citations

  3. Jichi Medical University

    Shimotsuke, Japan

    20 h-index

    65 publications

    3.3K citations

  4. Harvard University

    Cambridge, United States

    20 h-index

    79 publications

    8.9K citations

  5. University of Tübingen

    Tübingen, Germany

    17 h-index

    145 publications

    6.5K citations

  6. University of Oklahoma Health Sciences Center

    Oklahoma City, United States

    15 h-index

    44 publications

    4.2K citations

  7. Japan Science and Technology Agency

    Tokyo, Japan

    15 h-index

    54 publications

    10.2K citations

  8. University of California, San Francisco

    San Francisco, United States

    14 h-index

    59 publications

    8.4K citations

1–8 of 1K

Venues

  1. Kidney International

    20 publications · 2.8K citations

    19

    h-index

  2. PLoS ONE

    19 publications · 1.4K citations

    19

    h-index

  3. Journal of the American Society of Nephrology

    19 publications · 4.2K citations

    18

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 16 publications · 2.2K citations

    16

    h-index

  5. Scientific Reports

    18 publications · 597 citations

    14

    h-index

1–5