Concepedia

HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3

Sonja I. Gringhuis, Nina Hertoghs, Tanja M. Kaptein, Esther M. Zijlstra-Willems, Ramin Sarrami‐Forooshani, Joris K. Sprokholt, Nienke H. van Teijlingen, Neeltje A. Kootstra, Thijs Booiman, Karel A. van Dort,

Nature Immunology · 2016 · 137 citations · 40 references

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40

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

Fajian Hou, Lijun Sun, Hui Zheng et al. · Cell · 2011 · 1.3K citations · Full text

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Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

Daxing Gao, Jiaxi Wu, You-Tong Wu et al. · Science · 2013 · 988 citations

, , +15

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

Shaw-Yi Kao, Andrew F. Calman, Paul A. Luciw et al. · Nature · 1987 · 908 citations

, , +14

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

Hichem Lahouassa, Waaqo Daddacha, Henning Hofmann et al. · Nature Immunology · 2012 · 818 citations · Full text

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The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain

Andrew E. H. Elia, Peter Rellos, L.F. Haire et al. · Cell · 2003 · 769 citations · Full text

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