Tanja M. Kaptein

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

Sonja I. Gringhuis, Tanja M. Kaptein, Brigitte A. Wevers et al. · Nature Immunology · 2012 · 598 citations

Inflammation, Noncanonical Caspase-8 Inflammasome, Cytokine +9

Selective C-Rel Activation via Malt1 Controls Anti-Fungal TH-17 Immunity by Dectin-1 and Dectin-2

Sonja I. Gringhuis, Brigitte A. Wevers, Tanja M. Kaptein et al. · PLoS Pathogens · 2011 · 165 citations · Full text

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

Brigitte A. Wevers, Tanja M. Kaptein, Esther M. Zijlstra-Willems et al. · Cell Host & Microbe · 2014 · 147 citations · Full text

Antifungal Agent, Fungal Cell Biology, Antifungal Agents +7

Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation

Sonja I. Gringhuis, Tanja M. Kaptein, Brigitte A. Wevers et al. · Nature Communications · 2014 · 146 citations · Full text

Cyld-dependent Bcl3 Activation, Signal Transduction, Autoimmune Disease +12

HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3

Sonja I. Gringhuis, Nina Hertoghs, Tanja M. Kaptein et al. · Nature Immunology · 2016 · 136 citations · Full text

Host Helicase Ddx3, Viral Replication, Human Retrovirus +8