Sonja I. Gringhuis

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

Sonja I. Gringhuis, Tanja M. Kaptein, Brigitte A. Wevers et al. · Nature Immunology · 2012 · 598 citations

Inflammation, Noncanonical Caspase-8 Inflammasome, Cytokine +9

C-Type Lectin DC-SIGN Modulates Toll-like Receptor Signaling via Raf-1 Kinase-Dependent Acetylation of Transcription Factor NF-κB

Sonja I. Gringhuis, Jeroen den Dunnen, Manja Litjens et al. · Immunity · 2007 · 566 citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +15

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

Sonja I. Gringhuis, Jeroen den Dunnen, Manja Litjens et al. · Nature Immunology · 2009 · 468 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +13

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

Sonja I. Gringhuis, Jeroen den Dunnen, Manja Litjens et al. · Nature Immunology · 2009 · 435 citations

Pulmonary Tuberculosis, Signal Transduction, Mycobacterium Tuberculosis +9

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

Gerty Schreibelt, Gijs Kooij, Arie Reijerkerk et al. · The FASEB Journal · 2007 · 347 citations

Pi3 Kinase, Immunology, Bbb Integrity +29