Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature · 2005 · 2.7K citations

Medicine, Cancer Biology, Oncology +16

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis, Leandros-Vassilios Vassiliou, Panagiotis Karakaidos et al. · Nature · 2005 · 2K citations

Medicine, Molecular Biology, Oncology +16

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

Jiřina Bártková, Nousin Rezaei, Michalis Liontos et al. · Nature · 2006 · 2K citations

Medicine, Cancer Biology, Oncology +16

A Dominant Mutation That Predisposes to Multiple Intestinal Neoplasia in the Mouse

Amy Moser, Henry C. Pitot, William F. Dove · Science · 1990 · 1.6K citations

Medicine, Genetics, Oncology +17