Concepedia

Break-induced Replication

Break-Induced Replication is a DNA repair mechanism classified under homologous recombination, distinguished by its initiation at collapsed replication forks or double-strand breaks, where extensive DNA synthesis proceeds unidirectionally from a single broken end using a homologous template.

120

Publications

10.9K

Citations

631

Authors

249

Institutions

Publications per year

2017–2026

45

Variants

Bir

Parents

Publications

120

Break-induced replication and telomerase-independent telomere maintenance require Pol32

John R. Lydeard, Suvi Jain, Miyuki Yamaguchi et al. · Nature · 2007 · 487 citations

, , +13

Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

Lorenzo Costantino, Sotirios K. Sotiriou, Juha Rantala et al. · Science · 2013 · 448 citations · Full text

, , +17

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication.

Anna Malkova, E L Ivanov, James E. Haber · Proceedings of the National Academy of Sciences · 1996 · 407 citations

, , +17

Template switching during break-induced replication

Catherine E. Smith, Bertrand Llorente, Lorraine S. Symington · Nature · 2007 · 342 citations

, , +11

Migrating bubble during break-induced replication drives conservative DNA synthesis

Natalie Saini, Sreejith Ramakrishnan, Rajula Elango et al. · Nature · 2013 · 325 citations

, , +8

1–5 of 120

Authors

631

  1. AM
    Anna Malkova

    University of Iowa, United States

    17 publications · 2.4K citations

    16

    h-index

  2. JE
    James E. Haber

    Brandeis University, United States

    16 publications · 3.2K citations

    15

    h-index

  3. GI
    Grzegorz Ira

    Baylor College of Medicine, United States

    11 publications · 1.5K citations

    11

    h-index

  4. LS
    Lorraine S. Symington

    Columbia University Irving Medical Center, United States

    8 publications · 1K citations

    8

    h-index

  5. CJ
    Cynthia J. Sakofsky

    National Institute of Environmental Health Sciences, United States

    5 publications · 484 citations

    5

    h-index

1–5 of 631

Institutions

249

  1. Brandeis University

    Waltham, United States

    14 h-index

    51 publications

    9.1K citations

  2. Baylor College of Medicine

    Houston, United States

    12 h-index

    39 publications

    4.3K citations

  3. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    9 h-index

    30 publications

    5.1K citations

  4. University of Iowa

    Iowa City, United States

    8 h-index

    25 publications

    2.1K citations

  5. Columbia University Irving Medical Center

    New York, United States

    8 h-index

    26 publications

    2.4K citations

  6. Universidad de Sevilla

    Seville, Spain

    5 h-index

    12 publications

    711 citations

  7. National Institutes of Health

    Bethesda, United States

    4 h-index

    18 publications

    1.7K citations

  8. University of Oxford

    Oxford, United Kingdom

    4 h-index

    29 publications

    605 citations

1–8 of 249

Venues

  1. PLoS Genetics

    14 publications · 1K citations

    13

    h-index

  2. Nucleic Acids Research

    10 publications · 352 citations

    10

    h-index

  3. Nature Communications

    9 publications · 502 citations

    9

    h-index

  4. Molecular and Cellular Biology

    MCB · 8 publications · 1.1K citations

    8

    h-index

  5. Genetics

    7 publications · 568 citations

    7

    h-index

1–5