Concepedia

Negative regulation of NLRP3 inflammasome by SIRT1 in vascular endothelial cells

Yanxiang Li, Xiaofeng Yang, Yanhao He, Weirong Wang, Jiye Zhang, Wei Zhang, Ting Jing, Bo Wang, Rong Lin

Immunobiology · 2016 · 98 citations · 27 references

DOI

Concepts

References

27

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.8K citations

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae et al. · Nature Medicine · 2015 · 2.8K citations · Full text

, , +15

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

Christian Bauer, Peter Duewell, Christine Mayer et al. · Gut · 2010 · 908 citations · Full text

, , +17

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

Kairui Mao, Shuzhen Chen, Mingkuan Chen et al. · Cell Research · 2013 · 396 citations · Full text

, , +16

Vascular Smooth Muscle Cell Sirtuin 1 Protects Against DNA Damage and Inhibits Atherosclerosis

Isabelle Gorenne, Sheetal Kumar, Kelly Gray et al. · Circulation · 2012 · 270 citations

, , +17