The comparison of neuroprotective effects of isoliquiritigenin and its Phase I metabolites against glutamate-induced HT22 cell death

Structure-antioxidant activity relationships of flavonoids and phenolic acids

Catherine Rice‐Evans, Nicholas J. Miller, George Paganga · Free Radical Biology and Medicine · 1996 · 8.9K citations

Life Sciences, Biochemistry, Medicinal Chemistry +14

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

Timothy H. Murphy, Masaomi Miyamoto, Antonio Sastre et al. · Neuron · 1989 · 1K citations

Life Sciences, Neuroscience, Pharmacology +17

Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms

Kumiko Ishige, David Schubert, Yutaka Sagara · Free Radical Biology and Medicine · 2001 · 838 citations

Life Sciences, Neurobiology, Neuroscience +15

Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer

Balasundaram Padmanabhan, Kit I. Tong, Tsutomu Ohta et al. · Molecular Cell · 2006 · 731 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Carnosic acid, a <i>catechol‐type</i> electrophilic compound, protects neurons both <i>in vitro</i> and <i>in vivo</i> through activation of the Keap1/Nrf2 pathway via <i>S‐</i>alkylation of targeted cysteines on Keap1

Takumi Satoh, Kunio Kosaka, Ken Itoh et al. · Journal of Neurochemistry · 2007 · 387 citations

Life Sciences, Neurobiology, Neuroscience +14