Concepedia

Author

Kunio Kosaka

Nagase ChemteX (Japan)

Also Known As

Kunio Kosaka

33

Publications

1.6K

Citations

19

H-Index

41

Concepts

All Affiliations

Nagase ChemteX (Japan)Iwate UniversityHirosaki UniversityTohoku UniversityNagase (Japan)
KK

About

Kunio Kosaka is an author at Nagase ChemteX (Japan) specializing in medicine, biochemistry, and oxidative stress.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

11

11

713

2

Natural Sciences

4

4

213

3

Social Sciences

2

2

141

4

Engineering

1

1

19

5

Health Sciences

1

1

54

Kunio Kosaka

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20

Publications

1.6K

Citations

19

H-Index

YearCitations

Carnosic acid, a <i>catechol‐type</i> electrophilic compound, protects neurons both <i>in vitro</i> and <i>in vivo</i> through activation of the Keap1/Nrf2 pathway via <i>S‐</i>alkylation of targeted cysteines on Keap1

Takumi Satoh, Kunio Kosaka, Ken Itoh,

Journal of Neurochemistry

2007

377

Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism

Toshiyuki Takahashi, Takahito Tabuchi, Yosei Tamaki,

Biochemical and Biophysical Research Communications

2009

125

Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners

Takumi Satoh, Masanori Izumi, Yuki Inukai,

Neuroscience Letters

2008

118

Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells

Kunio Kosaka, Junsei Mimura, Ken Itoh,

The Journal of Biochemistry

2009

93

Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer’s disease models

Stuart A. Lipton, Tayebeh Rezaie, Anthony Nutter,

Cell Death and Disease

2016

87

Carnosic Acid, a Component of Rosemary (Rosmarinus officinalis L.), Promotes Synthesis of Nerve Growth Factor in T98G Human Glioblastoma Cells

Kunio Kosaka, Toshio Yokoi

Biological and Pharmaceutical Bulletin

2003

84

Effect of rosmarinic acid in motor dysfunction and life span in a mouse model of familial amyotrophic lateral sclerosis

Yosuke Shimojo, Kunio Kosaka, Yoshihiro Noda,

Journal of Neuroscience Research

2009

82

Carnosic acid prevents obesity and hepatic steatosis in <i>ob/ob</i> mice

Ting Wang, Yasuhiro Takikawa, Takumi Satoh,

Hepatology Research

2010

73

Protective Effect of Carnosic Acid, a Pro-Electrophilic Compound, in Models of Oxidative Stress and Light-Induced Retinal Degeneration

Tayebeh Rezaie, Scott R. McKercher, Kunio Kosaka,

Investigative Ophthalmology & Visual Science

2012

65

Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes

Junsei Mimura, Kunio Kosaka, Atsushi Maruyama,

The Journal of Biochemistry

2011

60

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