Site-selective enzymatic chemistry for polymer conjugation to protein lysine residues: PEGylation of G-CSF at lysine-41 - Concepedia

Concepedia

Abstract

Microbial transglutaminase (mTGase) is an enzyme that catalyzes site-specific protein derivatization at specific glutamines and lysines.

References

	Year	Citations
PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel Yong Zhang, Meirong Huo, Jianping Zhou, Computer Methods and Programs in Biomedicine Pharmacodynamic Data AnalysisPharmacokinetic ModelingDrug ResistanceMicrosoft ExcelPharmacology	2010	2K
An improved 2,4,6-trinitrobenzenesulfonic acid method for the determination of amines Stephen L. Snyder, P. Z. Sobocinski Analytical Biochemistry Chemical EngineeringChemical MeasurementEngineeringEnvironmental Analytical ChemistryOrganic Chemistry	1975	753
EFFECT OF GRANULOCYTE COLONY STIMULATING FACTOR ON NEUTROPENIA INDUCED BY CYTOTOXIC CHEMOTHERAPY George Morstyn, John Keech, William Sheridan, The Lancet InflammationGranulocyteMedicineImmunologyHematology	1988	734
Characterization and Stability of N-terminally PEGylated rhG-CSF Olaf Kinstler, David N. Brems, Scott L. Lauren, Pharmaceutical Research	1996	240
Site-Specific PEGylation of Protein Disulfide Bonds Using a Three-Carbon Bridge Sibu Balan, Ji-Won Choi, Antony Godwin, Bioconjugate Chemistry	2006	165
Polymeric Dibromomaleimides As Extremely Efficient Disulfide Bridging Bioconjugation and Pegylation Agents Mathew W. Jones, Rachel A. Strickland, Felix Schumacher, Journal of the American Chemical Society Salmon CalcitoninCombinatorial ChemistryEthylene GlycolBioorganic ChemistryPolymeric Dibromomaleimides	2011	157
Transglutaminase-Mediated PEGylation of Proteins: Direct Identification of the Sites of Protein Modification by Mass Spectrometry using a Novel Monodisperse PEG Anna Mero, Barbara Spolaore, Francesco M. Veronese, Bioconjugate Chemistry	2009	97
Further Studies on the Site-Specific Protein Modification by Microbial Transglutaminase Haruya Sato, Eiko Hayashi, Naoyuki Yamada, Bioconjugate Chemistry Chimeric ProteinsBioorganic ChemistryGlycobiologyMicrobial TransglutaminaseChemical Biology	2001	93
Site-Specific Pegylation of G-CSF by Reversible Denaturation Francesco M. Veronese, Anna Mero, Francesca Caboi, Bioconjugate Chemistry Protein ChemistryG-csf TendencyEthylene GlycolGlycosylationBiochemistry	2007	87
Selective conjugation of poly(2-ethyl 2-oxazoline) to granulocyte colony stimulating factor Anna Mero, Zhihao Fang, Gianfranco Pasut, Journal of Controlled Release Selective ConjugationEngineeringPolymer-drug ConjugateCell BiologyPolymer Chemistry	2012	80

Page 1