Concepedia

Site-selective enzymatic chemistry for polymer conjugation to protein lysine residues: PEGylation of G-CSF at lysine-41

Anna Mero, Antonella Grigoletto, Katia Maso, Hiroki Yoshioka, Antonio Rosato, Gianfranco Pasut

Polymer Chemistry · 2016 · 31 citations · 17 references

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Concepts

Abstract

Microbial transglutaminase (mTGase) is an enzyme that catalyzes site-specific protein derivatization at specific glutamines and lysines.

References

17

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

Yong Zhang, Meirong Huo, Jianping Zhou et al. · Computer Methods and Programs in Biomedicine · 2010 · 2K citations

, , +8

An improved 2,4,6-trinitrobenzenesulfonic acid method for the determination of amines

Stephen L. Snyder, P. Z. Sobocinski · Analytical Biochemistry · 1975 · 753 citations

, , +7

EFFECT OF GRANULOCYTE COLONY STIMULATING FACTOR ON NEUTROPENIA INDUCED BY CYTOTOXIC CHEMOTHERAPY

George Morstyn, John Keech, William Sheridan et al. · The Lancet · 1988 · 734 citations

, , +6

Characterization and Stability of N-terminally PEGylated rhG-CSF

Olaf Kinstler, David N. Brems, Scott L. Lauren et al. · Pharmaceutical Research · 1996 · 240 citations

Site-Specific PEGylation of Protein Disulfide Bonds Using a Three-Carbon Bridge

Sibu Balan, Ji-Won Choi, Antony Godwin et al. · Bioconjugate Chemistry · 2006 · 165 citations