Publication | Open Access

Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation

Histone ModificationsChromatinRecurrent MutationsChromatin RemodelingEpigenetic ChangeGeneticsGenomic MechanismMolecular BiologySet Domain ResidueMedicineEpigeneticsGenome EditingSetd2 Protein