Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair

Kayleigh A. Swaggart, Alexis R. Demonbreun, Andy H. Vo, +11

Proceedings of the National Academy of Sciences

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy

Mattia Quattrocelli, David Y. Barefield, James L. Warner, +5

Journal of Clinical Investigation

Enhances Muscle RepairGlucocorticoidOrthopaedic SurgeryMuscle AtrophyKinesiology +14

Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation

Kathryn E. Hacker, Catherine C. Fahey, Stephen A. Shinsky, +8

Journal of Biological Chemistry

Histone ModificationsChromatinRecurrent MutationsChromatin RemodelingEpigenetic Change +8

Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function

Yang Liu, Colin A. Kretz, Morgan L. Maeder, +10

Blood

Loss of Fibrinogen in Zebrafish Results in Symptoms Consistent with Human Hypofibrinogenemia

Andy H. Vo, Alok Swaroop, Yang Liu, +2

PLoS ONE

PathologyThrombosisHematologyZebrafish ResultsFish Immunology +16

Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ

Kay‐Marie Lamar, Sasha Bogdanovich, Brandon Gardner, +8

PLoS Genetics

Latent TgfβMuscle PhysiologyTranscriptional RegulationSignal TransductionMolecular Physiology +12

Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy

David Y. Barefield, Megan J. Puckelwartz, Ellis Y. Kim, +8

Circulation

Deep learning for cancer type classification and driver gene identification

Zexian Zeng, Chengsheng Mao, Andy H. Vo, +5

BMC Bioinformatics

Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury

Mattia Quattrocelli, Joanna Capote, Joyce C. Ohiri, +7

PLoS Genetics

Muscle FunctionBiomedical EngineeringOrthopaedic SurgeryCellular PhysiologyGenetic Disruption +17

Cancer classification and pathway discovery using non-negative matrix factorization

Zexian Zeng, Andy H. Vo, Chengsheng Mao, +3

Journal of Biomedical Informatics

Tumor BiologyEngineeringMatrix FactorizationData MiningComputational Biology +7