Concepedia

RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML

Leslie Crews, Larisa Balaian, Nathaniel P. Delos Santos, Heather Leu, Angela C. Court, Elisa Lazzari, Anil Sadarangani, M Zipeto, James J. La Clair, Reymundo Villa,

Cell stem cell · 2016 · 121 citations · 53 references

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53

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Siddhartha Jaiswal, Pierre Fontanillas, Jason Flannick et al. · New England Journal of Medicine · 2014 · 4.7K citations · Full text

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The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

Vidisha Tripathi, Jonathan D. Ellis, Zhen Shen et al. · Molecular Cell · 2010 · 2.2K citations · Full text

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Frequent pathway mutations of splicing machinery in myelodysplasia

Kenichi Yoshida, Masashi Sanada, Yuichi Shiraishi et al. · Nature · 2011 · 2.1K citations

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Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

Jianhui Chang, Yingying Wang, Lijian Shao et al. · Nature Medicine · 2015 · 1.8K citations

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