Concepedia

Development of a Pharmacokinetic Model to Describe the Complex Pharmacokinetics of Pazopanib in Cancer Patients

Nielka van Erp, Sander Bins, Ron H.J. Mathijssen, Jan H.M. Schellens, Jos H. Beijnen, Neeltje Steeghs, Alwin D. R. Huitema

Clinical Pharmacokinetics · 2016 · 49 citations · 22 references

DOI

Concepts

References

22

Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

Martin Bergstrand, Andrew C. Hooker, Johan Wallin et al. · The AAPS Journal · 2011 · 1.4K citations · Full text

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PsN-Toolkit—A collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM

Lars Lindbom, Pontus Pihlgren, E. Niclas Jonsson · Computer Methods and Programs in Biomedicine · 2005 · 1.1K citations

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Xpose—an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

E. Niclas Jonsson, Mats O. Karlsson · Computer Methods and Programs in Biomedicine · 1998 · 1K citations

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Phase I Trial of Pazopanib in Patients with Advanced Cancer

Herbert I. Hurwitz, Afshin Dowlati, Shermini Saini et al. · Clinical Cancer Research · 2009 · 413 citations · Full text

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Simultaneous vs. Sequential Analysis for Population PK/PD Data I: Best-Case Performance

Liping Zhang, Stuart L. Beal, Lewis B. Sheiner · Journal of Pharmacokinetics and Pharmacodynamics · 2003 · 368 citations

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