Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats

Mingming Zhang, Qian Zhou, Robert Dorfman, Xiaoli Huang, Tingting Fan, Hao Zhang, Jun Zhang, Chenggong Yu

BMC Gastroenterology · 2016 · 200 citations · 23 references

DOIFull text

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Abstract

Our results suggest that butyrate plays a key role in regulating the Treg/Th17 balance and ultimately protects the colon mucosa against the development of IBD.

References

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