Mulberry anthocyanin extract ameliorates insulin resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db mice

Global Prevalence of Diabetes

Sarah H. Wild, Gojka Roglić, Anders Green et al. · Diabetes Care · 2004 · 15.3K citations

Public Health, Demography, Population Health Sciences +12

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki et al. · Nature Medicine · 2001 · 4.9K citations

Medicine, Biochemistry, Endocrinology +14

Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice

Hong Chen, Olga Charlat, Louis A. Tartaglia et al. · Cell · 1996 · 2.2K citations · Full text

Life Sciences, Endocrinology, Genetics +11

Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction

Pere Puigserver, James Rhee, Jerry Donovan et al. · Nature · 2003 · 1.5K citations

Life Sciences, Endocrinology, Molecular Biology +14

AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells

Mengwei Zang, Adriana Zuccollo, Xiuyun Hou et al. · Journal of Biological Chemistry · 2004 · 454 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14