ImmunoPEGliposome-mediated reduction of blood and brain amyloid levels in a mouse model of Alzheimer's disease is restricted to aged animals

Global prevalence of dementia: a Delphi consensus study

Cleusa P. Ferri, Martin Prince, Carol Brayne et al. · The Lancet · 2005 · 5.3K citations · Full text

Medicine, Geriatric Medicine, Neurology +11

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations

Life Sciences, Neurology, Neuroscience +17

Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

Takeshi Iwatsubo, Asano Odaka, Nobuhiro Suzuki et al. · Neuron · 1994 · 1.8K citations

Life Sciences, Neuroscience, Pathology +16

Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

James Cleary, Dominic M. Walsh, J. Hofmeister et al. · Nature Neuroscience · 2004 · 1.7K citations

Life Sciences, Molecular Biology, Neuroscience +16

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

Ronald B. DeMattos, Kelly R. Bales, David J. Cummins et al. · Proceedings of the National Academy of Sciences · 2001 · 1.3K citations · Full text

Pharmacy, Neurobiology, Neuroscience +17