Concepedia

Protein kinase CK2 regulates AKT, NF-κB and STAT3 activation, stem cell viability and proliferation in acute myeloid leukemia

Laura Quotti Tubi, Sara Canovas Nunes, Alessandra Brancalion, E Doriguzzi Breatta, Sabrina Manni, Elisa Mandato, Fortunato Zaffino, Paolo Macaccaro, Marilena Carrino, Ketty Gianesin,

Leukemia · 2016 · 71 citations · 34 references

DOI

Concepts

References

34

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Tsvee Lapidot, Christian Sirard, Josef Vormoor et al. · Nature · 1994 · 4.7K citations

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Hedgehog Signaling and Bmi-1 Regulate Self-renewal of Normal and Malignant Human Mammary Stem Cells

Suling Liu, Gabriela Dontu, Ilia D. Mantle et al. · Cancer Research · 2006 · 1.2K citations · Full text

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Targeting of CD44 eradicates human acute myeloid leukemic stem cells

Liqing Jin, Kristin J. Hope, Qiongli Zhai et al. · Nature Medicine · 2006 · 1.2K citations

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Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization

Jochen Schust, Bianca Sperl, Angela Hollis et al. · Chemistry & Biology · 2006 · 1.1K citations

, , +11