Concepedia

Publication | Open Access

The Novel KLF4/MSI2 Signaling Pathway Regulates Growth and Metastasis of Pancreatic Cancer

DOIFull Paper Access

83

Citations

37

References

2016

Year

Kun Guo, Jiujie Cui, Ming Quan, Dacheng Xie, Zhiliang Jia, Daoyan Wei, Liang Wang, Yong Gao, Qingyong Ma, Keping Xie
Clinical Cancer Research

Abstract

Lost expression of KLF4, a transcriptional repressor of MSI2 results in overexpression of MSI2 in PDACs, which may be a biomarker for accurate prognosis. A dysregulated KLF4/MSI2 signaling pathway promotes PDAC progression and metastasis. Clin Cancer Res; 23(3); 687-96. ©2016 AACR.

References

YearCitations

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