Michael G. Kharas

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

Ly Vu, Brian F. Pickering, Yuanming Cheng et al. · Nature Medicine · 2017 · 1.3K citations · Full text

Hematological Malignancy, Chromatin, Myeloid Differentiation +12

The Lin28/let-7 Axis Regulates Glucose Metabolism

Hao Zhu, Ng Shyh‐Chang, Ayellet V. Segrè et al. · Cell · 2011 · 890 citations · Full text

Diabetes, Metabolic Regulation, Metabolic Control +5

PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer

Ana Bosch, Zhiqiang Li, Anna Bergamaschi et al. · Science Translational Medicine · 2015 · 418 citations · Full text

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

Michael G. Kharas, Christopher J. Lengner, Fátima Al‐Shahrour et al. · Nature Medicine · 2010 · 393 citations · Full text

Hematological Malignancy, Hematology, Medicine +3

Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells

Ann Mullally, Steven Lane, Brian Ball et al. · Cancer Cell · 2010 · 384 citations · Full text

Progenitor Cells, Hematological Malignancy, Medicine +13