Concepedia

Publication | Open Access

Epigenetic silencing of serine protease HTRA1 drives polyploidy

DOIFull Paper Access

26

Citations

19

References

2016

Year

Nina Schmidt, Inga Irle, Kamilla Ripkens, Vanda Lux, Jasmin Nelles, Christian Johannes, Lee Parry, Kirsty R. Greenow, Sarah Amir, Mara Campioni,
BMC Cancer

Abstract

Downregulation of HTRA1 causes a number of phenotypes that are hallmarks of cancer cells suggesting that the methylation state of the HtrA1 promoter may be used as a biomarker for tumour cells or cells at risk of transformation.

References

YearCitations

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