Bioinformatics · 2016 · 178 citations · 14 references
Life SciencesBioinformaticsVisualizationData VisualizationGenome AssemblyGenomicsDe Novo Genome AssemblyDna SequencingGenome SequencingGenome VisualizationGenomic Data VisualizationSequence VisualizationInteractive Genomic VisualizationInteractive Visualization ToolsQuality Assessment
: Data visualization plays an increasingly important role in NGS data analysis. With advances in both sequencing and computational technologies, it has become a new bottleneck in genomics studies. Indeed, evaluation of de novo genome assemblies is one of the areas that can benefit from the visualization. However, even though multiple quality assessment methods are now available, existing visualization tools are hardly suitable for this purpose. Here, we present Icarus-a novel genome visualizer for accurate assessment and analysis of genomic draft assemblies, which is based on the tool QUAST. Icarus can be used in studies where a related reference genome is available, as well as for non-model organisms. The tool is available online and as a standalone application. AVAILABILITY AND IMPLEMENTATION: http://cab.spbu.ru/software/icarus CONTACT: aleksey.gurevich@spbu.ruSupplementary information: Supplementary data are available at Bioinformatics online.
14
QUAST: quality assessment tool for genome assemblies
Alexey Gurevich, Vladislav Saveliev, Nikolay Vyahhi et al. · Bioinformatics · 2013 · 11.5K citations · Full text
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs
Daniel R. Zerbino, Ewan Birney · Genome Research · 2008 · 9.7K citations · Full text
Versatile and open software for comparing large genomes
Stefan Kurtz, Adam M. Phillippy, Arthur L. Delcher et al. · Genome biology · 2004 · 5.8K citations · Full text
ABySS: A parallel assembler for short read sequence data
Jared T. Simpson, Kim Wong, Shaun D. Jackman et al. · Genome Research · 2009 · 3.8K citations · Full text
Life Sciences, Biology, Genetics +17